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Ceebis 20 Mg is a prescription medication manufactured by Cooper Pharma that contains 20 mg of tadalafil, a phosphodiesterase type 5 (PDE5) inhibitor. It is primarily used to treat erectile dysfunction (ED) in adult males. Ceebis improves blood flow to the penis during sexual arousal, helping achieve and maintain an erection. It is also indicated for the treatment of benign prostatic hyperplasia (BPH) and pulmonary arterial hypertension (PAH). Ceebis typically begins working within 30 to 60 minutes and remains effective for up to 36 hours, earning it the nickname “weekend pill.” Ceebis is not intended for use in women or children.
Contains
Tadalafil
Treats
Erectile Dysfunction, BPH, PAH
Lasts
36 hours
Manufactured By
Cooper Pharma
Ceebis 20mg is a tadalafil-based oral medication prescribed for erectile dysfunction. Each Ceebis 20mg tablet contains tadalafil, a selective inhibitor of phosphodiesterase type 5 (PDE5). By blocking PDE5, the drug increases levels of cyclic guanosine monophosphate (cGMP) in the smooth muscle of the penis, allowing for improved blood flow during sexual stimulation. Ceebis does not trigger an erection on its own; it only enhances the natural erectile response when sexual arousal is present. Ceebis belongs to the pharmacological class of PDE5 inhibitors and is available only by prescription.
Ceebis 20mg is used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension. Tadalafil, the active ingredient in Ceebis 20mg, is approved by the FDA for three primary indications:
Ceebis 20mg typically takes 30 to 60 minutes to become effective after ingestion. Ceebis 20mg works by inhibiting phosphodiesterase type 5 (PDE5), an enzyme that degrades cyclic guanosine monophosphate (cGMP). During sexual arousal, nitric oxide (NO) is released by nerve terminals and endothelial cells in the penis. NO stimulates guanylate cyclase, increasing cGMP synthesis. Elevated cGMP levels cause smooth muscle relaxation in the corpus cavernosum, enhancing blood flow and enabling an erection.
Tadalafil blocks PDE5 from breaking down cGMP, thereby prolonging and intensifying this vasodilatory effect. However, sexual stimulation is essential; without arousal and NO release, tadalafil has no effect.
Compared to sildenafil and vardenafil, tadalafil has a longer half-life (17.5 hours), which explains its prolonged duration of action and suitability for daily dosing or weekend use. The rate of onset may vary based on individual metabolic rate, food intake, and overall health status.
The effects of Ceebis 20mg can last up to 36 hours. Tadalafil’s long half-life supports sustained cGMP levels in the corpus cavernosum, allowing users to respond to sexual stimulation over an extended period. The peak concentration of tadalafil in plasma typically occurs within 2 hours of ingestion. Though detectable for over a day, the therapeutic effect gradually diminishes as the drug is metabolized. Individual response may vary based on factors such as age, liver function, cardiovascular health, and tolerance to PDE5 inhibitors. Importantly, sexual arousal remains a necessary trigger for efficacy throughout this window.
The standard dose of Ceebis is one 20 mg tablet taken once in a 24-hour period. Patients should take Ceebis approximately 30 to 60 minutes before anticipated sexual activity. The tablet should not be taken more than once per day. Dosage adjustments must be made under medical supervision, especially for patients with renal or hepatic impairment, or those on interacting medications. Exceeding the prescribed dose increases the risk of adverse effects without improving efficacy.
Swallow the Ceebis tablet whole with water, preferably on an empty stomach. While Ceebis may be taken with or without food, high-fat meals may delay its absorption. For optimal results, avoid fatty foods and consume the tablet at least one hour before planned sexual activity. Do not crush or split the tablet. Alcohol use should be limited during treatment, as it can interfere with tadalafil’s action and increase the risk of hypotension and dizziness.
Ceebis 20mg may cause mild to moderate side effects, most of which resolve over time.
Common Side Effects
Less Common Side Effects
Rare Side Effects
Seek immediate medical attention if experiencing chest pain, severe dizziness, sudden visual changes, or an erection lasting more than 4 hours.
Ceebis may interact with drugs that affect cardiovascular function, liver enzymes, or blood pressure.
Drug/Category | Interaction Effect |
---|---|
Nitrates | Severe hypotension; contraindicated |
Alpha-blockers | Additive hypotensive effect; use with caution |
Antihypertensives | Small additional BP drop; monitor closely |
Alcohol | Enhanced vasodilation; increased dizziness and heart rate |
Antacids | Slows absorption; does not alter overall exposure |
CYP3A4 Inhibitors (e.g., ketoconazole, ritonavir) | Increases tadalafil plasma levels significantly |
CYP3A4 Inducers (e.g., rifampin, phenytoin) | Decreases tadalafil levels; may reduce efficacy |
Warfarin, theophylline, midazolam, lovastatin | No significant interaction expected |
Digoxin | No significant change in pharmacokinetics |
Patients must inform their physician of all prescription and non-prescription drugs they are taking to avoid interactions.
Ceebis 20mg can be taken with or without food, but alcohol should be consumed in moderation. While food does not significantly affect the drug’s bioavailability, a high-fat meal can delay the onset of action. Alcohol, especially in large quantities, can amplify the risk of hypotension, dizziness, and fainting. For maximum effectiveness and safety, avoid excessive alcohol intake when using Ceebis.
Follow these guidelines to preserve the effectiveness of Ceebis 20mg:
Published on: April 28, 2022
Last Modified on: June 2, 2025
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