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Cenforce Soft is a chewable tablet containing 100 mg of sildenafil citrate per unit. Centurion Laboratories manufactures Cenforce Soft as a prescription medication for erectile dysfunction (ED) in men. Sildenafil citrate inhibits phosphodiesterase type 5 (PDE5), promoting penile blood flow during sexual arousal. Cenforce Soft is a generic equivalent of Viagra. Each blister pack includes 10 tablets. The onset of action occurs within 15 to 30 minutes. Duration of effect ranges from 4 to 6 hours. Cenforce Soft is contraindicated for use in women and pediatric patients.
Cenforce Soft is a chewable PDE5 inhibitor used to treat erectile dysfunction in men.
Its active ingredient is 100mg of Sildenafil Citrate, a selective inhibitor of phosphodiesterase type 5 (PDE5). By enhancing the natural nitric oxide cGMP pathway, it increases blood flow to the penile tissue during sexual stimulation. Cenforce Soft promotes vasodilation in the corpus cavernosum, which leads to a firm and sustained erection. The drug is available as a fast-dissolving chewable tablet, offering a convenient option for patients with difficulty swallowing traditional pills.
Cenforce Soft is prescribed for the treatment of erectile dysfunction (ED) and pulmonary arterial hypertension (PAH). Erectile dysfunction is defined as the persistent inability to achieve or maintain an erection sufficient for satisfactory sexual performance. Cenforce Soft does not cure ED but improves the erectile response during sexual stimulation. It is also used off-label in the management of pulmonary arterial hypertension, a condition characterised by elevated blood pressure in the pulmonary arteries.
Cenforce Soft typically starts working within 15 to 30 minutes after oral administration.
This time may vary based on factors such as individual metabolism, diet, and general health. Sildenafil Citrate, the active ingredient in Cenforce Soft, acts by inhibiting PDE5 in the corpus cavernosum of the penis. PDE5 is an enzyme that breaks down cyclic guanosine monophosphate (cGMP), a molecule involved in smooth muscle relaxation.
Sexual stimulation releases nitric oxide (NO), which binds to guanylate cyclase in smooth muscle cells. This increases cGMP production, which in turn activates protein kinase G (PKG). PKG phosphorylates targets such as myosin light chain phosphatase, phospholipase C, and RhoA. These actions reduce intracellular calcium levels and desensitize calcium-mediated contractions. The resulting smooth muscle relaxation causes dilation of the helicine arteries and enhances blood inflow to the corpus cavernosum. Sildenafil mimics cGMP in structure and competitively binds to PDE5, preventing cGMP degradation. This leads to an amplified and prolonged erectile response during sexual arousal.
Sildenafil is metabolized primarily in the liver by CYP3A4 and secondarily by CYP2C9. Its major metabolite, N-desmethylated sildenafil, retains partial PDE5 inhibitory activity and contributes to the drug’s therapeutic effects. Sildenafil and its metabolites are excreted primarily in the feces and to a lesser extent in the urine.
The effects of Cenforce Soft generally last between 4 to 6 hours. This duration may vary based on the user’s age, health status, and metabolic rate. Sildenafil has a terminal half-life of approximately 3 to 5 hours. Peak plasma concentration is typically reached within 1 hour under fasting conditions. The presence of a high-fat meal can delay absorption and lower peak levels. The drug is effective only in the presence of sexual stimulation.
The standard dose of Cenforce Soft is 100 mg, taken once in a 24-hour period. It should be taken approximately 30 to 60 minutes before anticipated sexual activity. Do not exceed one dose in 24 hours. Dose adjustments may be required for patients with hepatic or renal impairment, or when used with interacting medications. Always follow the prescribing physician’s dosage instructions.
Cenforce Soft should be taken orally by chewing the tablet, with or without water.
It is best taken on an empty stomach for faster onset. Taking the tablet after a high-fat meal may delay its effect. Take the medication about one hour before planned sexual activity. Do not consume more than one dose in a 24-hour period.
Cenforce Soft may cause side effects, most of which are mild and self-limiting. These effects usually decrease as the body adjusts to the medication.
Common Side Effects
Less Common Side Effects
Rare Side Effects
Seek immediate medical help if any rare or severe effects occur.
Cenforce Soft interacts with drugs that affect cardiovascular health or liver enzymes.
These interactions can alter efficacy or increase the risk of side effects.
Drug Category | Examples | Effect of Interaction |
---|---|---|
Nitrates | Nitroglycerin, Isosorbide | Severe hypotension |
Alpha-blockers | Tamsulosin, Doxazosin | Dizziness, fainting |
Antifungals | Ketoconazole, Itraconazole | Increased Sildenafil levels |
Antibiotics | Erythromycin, Clarithromycin | Delayed metabolism, increased side effects |
Antivirals | Ritonavir, Saquinavir | Enhanced duration and plasma concentration |
Other ED Drugs | Tadalafil, Vardenafil | Risk of cumulative side effects |
Recreational Nitrates | Poppers (Amyl nitrate) | Life-threatening drop in blood pressure |
Cenforce Soft can be taken with or without food, but fatty meals may delay its action.
Food, particularly high-fat meals, slows down the absorption rate and reduces peak plasma levels. Alcohol consumption may reduce the drug’s effectiveness and increase the risk of side effects such as dizziness or hypotension. For best results, limit or avoid alcohol use.
Store Cenforce Soft as per standard pharmaceutical guidelines to preserve its potency.
Published on: June 3, 2025
Last Modified on: July 8, 2025
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