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Fildena 25 mg is a prescription medication produced by Fortune Healthcare. It contains sildenafil citrate, a phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction (ED) in men. As a generic version of Viagra, it works by improving blood flow to the penis during sexual stimulation. The tablet starts working within 30 to 60 minutes and typically remains effective for 4 to 6 hours. Fildena 25 mg is not intended for use in women or children. Each blister strip contains 10 tablets. It should be taken only under medical supervision and as prescribed for erectile dysfunction management.
Fildena 25 mg is a prescription medication that contains sildenafil citrate, the same active ingredient found in Viagra. It belongs to a class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors. Fildena 25 mg is used in men for the treatment of erectile dysfunction, a condition characterized by the inability to achieve or maintain an erection sufficient for sexual intercourse. This drug does not cause an erection on its own but enhances erectile response by increasing blood flow to the penis when sexual stimulation occurs.
Fildena 25 mg is used to treat erectile dysfunction (ED) in adult men. Erectile dysfunction is defined as the consistent inability to achieve or sustain an erection adequate for satisfactory sexual performance. Fildena 25 mg helps improve erectile quality during sexual arousal but does not cure ED. It restores erectile function temporarily by supporting natural erection mechanisms during intimacy.
Fildena 25 mg typically starts working within 30 to 60 minutes after ingestion. Its onset may vary depending on an individual’s metabolism, overall health, and whether the tablet is taken with food. It works by enhancing the nitric oxide–cGMP pathway, which is central to the erectile response.
Sexual stimulation releases nitric oxide (NO) in the corpus cavernosum. NO activates guanylate cyclase, which increases cyclic guanosine monophosphate (cGMP). This biochemical cascade causes the smooth muscle in penile blood vessels to relax, promoting increased blood flow into the corpus cavernosum and resulting in an erection.
Sildenafil, the active ingredient in Fildena 25 mg, selectively inhibits PDE5, the enzyme responsible for cGMP degradation. By preventing cGMP breakdown, sildenafil prolongs smooth muscle relaxation and blood engorgement in the penis during sexual arousal.
This molecular mechanism also involves cGMP-dependent protein kinase (PKG), which phosphorylates various targets such as myosin light chain phosphatase and the IP3 receptor. These actions reduce intracellular calcium levels, further promoting vasodilation. Without sexual stimulation and the resulting nitric oxide release, Fildena 25 mg will not be effective.
Sildenafil is primarily metabolized by liver enzymes CYP3A4 and CYP2C9. Its major active metabolite, N-desmethylated sildenafil, has about 40% of the parent compound’s PDE5 inhibitory activity and contributes to the overall pharmacological effect. About 80% of the drug is excreted in the feces and 13% in the urine.
The effects of Fildena 25 mg usually last between 4 to 6 hours. The duration can vary depending on age, health status, metabolic rate, and other medications taken. The half-life of sildenafil is approximately 3 to 5 hours, with peak plasma concentrations typically reached in about 60 minutes. Despite this window, an erection will only occur with sexual stimulation. The drug does not cause continuous erections or increase sexual desire independently.
Fildena 25 mg is generally prescribed as a starting dose for men who are new to sildenafil therapy or who are sensitive to medication. It should be taken once per day, about 30 to 60 minutes before planned sexual activity. The dosage should not exceed one tablet in a 24-hour period. Patients should consult their healthcare provider to determine if a dosage adjustment is needed based on efficacy and tolerability.
Fildena 25 mg should be swallowed whole with water. It can be taken with or without food, though taking it on an empty stomach may result in faster absorption. A heavy or fatty meal may delay the onset of action. For optimal results, take the tablet approximately one hour before sexual activity. Do not take more than one dose in a 24-hour period, and always follow your doctor’s instructions.
Fildena 25 mg may cause side effects, most of which are mild and temporary as the body adapts to the medication.
Common Side Effects:
Less Common Side Effects:
Rare Side Effects:
Seek immediate medical help if any severe or rare side effects occur.
Fildena 25 mg can interact with several medications and substances, affecting its efficacy and safety. Always inform your doctor of any medications or supplements you are taking.
Drug Category | Examples | Effect of Interaction |
---|---|---|
Nitrates | Nitroglycerin, Isosorbide Mononitrate | Severe drop in blood pressure |
Alpha-blockers | Tamsulosin, Doxazosin | Increased risk of dizziness or fainting |
Antifungals | Ketoconazole, Itraconazole | Elevated sildenafil levels |
Antibiotics | Erythromycin, Clarithromycin | Slower metabolism, increased side effects |
Antivirals | Ritonavir, Saquinavir | Prolonged action and elevated plasma concentration |
Other ED Drugs | Tadalafil, Vardenafil | Enhanced risk of side effects |
Recreational Nitrates | Poppers (Amyl nitrate) | Life-threatening hypotension |
Fildena 25 mg can be taken with or without food. However, a high-fat meal may slow absorption and delay the drug’s onset of action. Alcohol should be avoided or consumed in moderation, as it can impair the effectiveness of the medication and increase the risk of dizziness, low blood pressure, and other adverse effects. For best results, limit alcohol intake when using this medication.
Follow the storage instructions listed below to ensure the maximum potency of your drug.
Published on: May 31, 2025
Last Modified on: July 8, 2025
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