What is Sildigra 100 mg?
Sildigra 100 mg is an oral prescription medication containing Sildenafil Citrate 100 mg, used to treat erectile dysfunction (ED) in adult men. This formulation is classified as a phosphodiesterase type 5 (PDE5) inhibitor. It is designed to enhance blood flow to the penis during sexual stimulation, allowing men to achieve and maintain a firm erection. Manufactured by Cipla, Sildigra is available in tablet form and typically comes in blister packs of 10.
Sildigra 100 mg is considered a generic alternative to Viagra, offering the same active ingredient and therapeutic benefits at a potentially lower cost. It is most effective when taken on an empty stomach 30 to 60 minutes before sexual activity. However, it does not increase libido and requires sexual arousal to be effective.
What is Sildigra 100 mg Used For?
Sildigra 100 mg is prescribed to treat erectile dysfunction (ED), a condition where a man is consistently unable to achieve or maintain an erection sufficient for sexual performance. It is not intended for daily use or as a treatment for libido loss or premature ejaculation.
Sildigra is not intended for use in pulmonary arterial hypertension (PAH). Lower-dose sildenafil formulations are used for that condition. Do not use Sildigra in combination with other sildenafil-containing drugs to avoid the risk of overdose.
How Does Sildigra 100 mg Work?
Sildigra 100 mg works by increasing blood flow to the penis during sexual stimulation, allowing for a firm and sustained erection. Its active ingredient, Sildenafil Citrate, is a phosphodiesterase type 5 (PDE5) inhibitor. During sexual arousal, nitric oxide is released in the erectile tissue of the penis. This triggers the production of cyclic guanosine monophosphate (cGMP), a molecule that relaxes the smooth muscles in the blood vessel walls, enabling increased blood flow into the corpus cavernosum.
Under normal conditions, the enzyme PDE5 breaks down cGMP, ending the erection. Sildigra blocks PDE5, allowing cGMP to accumulate and persist longer in the erectile tissue. As a result, the blood vessels remain dilated, helping to maintain an erection long enough for sexual activity. However, this mechanism is activated only in the presence of sexual stimulation; Sildigra does not work in the absence of arousal.
How Long Does Sildigra 100 mg Last?
The effects of Sildigra 100 tablets generally last between 4 to 6 hours after ingestion. The onset of action typically occurs within 30 to 60 minutes. Factors such as metabolism, food intake, and overall health can influence the onset and duration. It is important to note that sexual stimulation is necessary for Sildigra 100 to produce an erection at any time during its effective window.
| Parameter | Details |
|---|---|
| Onset | 30 to 60 minutes after ingestion |
| Duration | 4 to 6 hours |
| Influencing Factors | Details |
|---|---|
| Age & Health | Older age or certain conditions may slow effect |
| Metabolic Rate | Faster metabolism may reduce duration |
| Food Intake | High-fat meals can delay absorption |
| Other Medications | Some drugs can enhance or reduce effectiveness |
Remember: Sexual arousal is required for the medication to be effective.
What is the Recommended Dosage of Sildigra 100?
The recommended dosage of Sildigra 100 is one tablet (100 mg) taken as needed, approximately 30 to 60 minutes before sexual activity. It should not be taken more than once per day. Patients who are new to sildenafil should consult a healthcare provider before using this high-strength dose, as a lower strength might be more appropriate initially. Dosage adjustments should only be made under medical supervision.
How to Take Sildigra 100 mg?
Take one Sildigra 100 mg tablet on an empty stomach, approximately 30 to 60 minutes before planned sexual activity. Avoid consuming alcohol, grapefruit juice, or high-fat meals, as these can interfere with the medication’s action. Do not exceed one tablet within 24 hours to prevent the risk of side effects.
What Are the Side Effects of Sildigra 100 mg?
Sildigra 100, like all medications containing sildenafil, can cause side effects. Most side effects are mild and temporary, but some may require medical attention. The following symptoms are commonly reported side effects of Sildigra 100mg:
- Headache
- Flushing (facial redness)
- Nasal congestion
- Dizziness
- Nausea
- Indigestion
- Vision changes (blurred vision or color tinge)
The following symptoms are rare but serious side effects:
- Priapism (painful erection lasting over 4 hours)
- Chest pain
- Sudden vision or hearing loss
- Severe allergic reactions
Seek immediate medical help if any serious side effects occur.
What are the Drug Interactions of Sildigra 100?
Sildigra 100 may interact with certain drugs and substances, which could either potentiate side effects or reduce its efficacy. Refer to the tabular representation below for the list of drugs that can interact with Sildigra.
| Drug Class / Substance | Interaction Type | Effect / Risk |
|---|---|---|
| Nitrates (e.g., nitroglycerin) | Contraindicated | Dangerous drop in blood pressure |
| Alpha-blockers (e.g., doxazosin) | Caution advised | Increased risk of hypotension |
| Other PDE5 inhibitors | Avoid combination | Increased risk of adverse effects |
| Antihypertensives | Additive effect | May enhance blood pressure-lowering |
| CYP3A4 inhibitors (e.g., ketoconazole, ritonavir) | Increased sildenafil levels | Higher risk of side effects |
| CYP3A4 inducers (e.g., rifampicin) | Decreased sildenafil levels | Reduced efficacy |
| Alcohol | Exacerbates side effects | Increases dizziness and hypotension |
| Recreational drugs (e.g., poppers) | Contraindicated | Severe hypotension risk |
Always consult a healthcare professional before combining Sildigra 100 with any other medications or substances.
How Should Sildigra 100 be Stored?
To maintain its effectiveness, follow the instructions listed below.
- Store at room temperature between 20°C to 25°C (68°F to 77°F).
- Keep in a dry place away from moisture and humidity.
- Protect from direct sunlight and excessive heat.
- Keep out of reach of children and pets.
- Store tablets in their original packaging until use.
- Do not use after the expiry date printed on the blister pack.
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