Super P Force Tablets (Sildenafil+ Dapoxetine)

How does it Work?

Super P Force contains two active ingredients: sildenafil citrate and dapoxetine. Sildenafil works by inhibiting the action of the PDE5 enzyme. This allows cyclic guanosine monophosphate (cGMP) to accumulate in the smooth muscle cells of the penis. It leads to relaxation of the blood vessels and increased blood flow. This results in an erection during sexual stimulation.

Dapoxetine works by inhibiting the reuptake of serotonin. It is a neurotransmitter involved in the ejaculatory process. By increasing serotonin levels in the brain, dapoxetine can help delay premature ejaculation and improve control over ejaculation.

Uses

Super P Force is used in the treatment of

1. Erectile dysfunction (ED)
2. Premature Ejaculation (PE)

Recommended Dose

The recommended dosage of Super P Force is usually one tablet in 24 hours. It is taken orally with a full glass of water approximately 1 to 3 hours before anticipated sexual activity. Do not exceed one tablet within 24 hours to avoid the risk of side effects. Take Super P Force as directed by your healthcare provider, and do not adjust the dosage without consulting them first.

Missed Dose

If you miss a dose, you can take it as soon as you remember. Unless it is time for your next scheduled dose, in that case skip the missed dose. Do not double dose to compensate for a missed dose.

Overdose

Taking more than the recommended dose can increase the risk of side effects and complications. If you suspect an overdose, seek medical attention immediately.

Side Effects

The most common side effects include:

• Increased blood pressure
• Increased heart rate
• Priapism (prolonged, painful erection)
• Serotonin syndrome (confusion, agitation, sweating, tremors)
• Vision changes
• Headaches
• Dizziness
• Nausea/Vomiting
• Flushing

Rare but Serious Side Effects:

• Hearing loss
• Chest pain
• Irregular heartbeat
• Stroke
• Heart attack
• Seizures
• Allergic reactions

Safety Advice

Super P Force should be used with caution and under medical supervision. Follow your doctor’s instructions carefully and report any adverse effects promptly. Here are some safety precautions to keep in mind:

• Do not take Super P Force if you are allergic to sildenafil, or dapoxetine.
• Avoid taking Super P Force if you are taking nitrates for chest pain or heart problems. This combination can cause a dangerous drop in blood pressure.
• Inform your doctor if you have a history of heart disease, stroke, low blood pressure, or bleeding disorders.
• Inform your doctor if you have liver or kidney disease, or any other medical conditions.
• Super P Force may cause dizziness or blurred vision. Caution is advised when driving or operating machinery.
• Excessive alcohol consumption can increase the risk of side effects. It may also impair the ability to achieve an erection or delay ejaculation.
• Super P Force should not be taken by women or children.

Medical Interactions

Super P Force may interact with other medications and alter its effectiveness or increase the risk of side effects. Inform your doctor about all the medications you are taking to avoid potential interactions. This includes prescription drugs, over-the-counter medications, vitamins, and herbal supplements.

Some significant drug interactions include:

• nitrates (amyl nitrite and nitroglycerin),
• monoamine oxidase inhibitors (MAOI)
• alpha-blockers
• antidepressants (lithium and hypericum perforatum),
• antibiotic (linezolid),
• pain killer (tramadol),
• a medicine that regulates sleep (tryptophan),
• medicines used to treat migraine
• antifungal agents (ketoconazole and itraconazole),
• HIV medicines (ritonavir, saquinavir, and atazanavir, etc.),
• antibiotic (telithromycin),
• high blood pressure medicines (alfuzosin, doxazosin, and tamsulosin, etc.)
• selective serotonin reuptake inhibitors (SSRIs)
• serotonin-norepinephrine reuptake inhibitors (SNRIs)

Storage

Follow these storage guidelines to keep the tablets effective and intact for a longer time-

• Store at room temperature.
• Keep the medication in its original packaging tightly closed.
• Protect from light, moisture, and excessive heat.
• Do not store in the bathroom or near a sink, as the moisture and heat can degrade the medication.
• Keep out of reach of children and pets.
• Do not use the medication after the expiration date printed on the package or container.

FAQs

Refrences

1. Abu El-Hamd M, Abdelhamed A. Comparison of the clinical efficacy and safety of the on-demand use of paroxetine, dapoxetine, sildenafil and combined dapoxetine with sildenafil in treatment of patients with premature ejaculation: A randomised placebo-controlled clinical trial. Andrologia. 2018 Feb;50(1). doi: 10.1111/and.12829. Epub 2017 May 12. PMID: 28497478.https://onlinelibrary.wiley.com/doi/10.1111/and.12829
2. Attala K, Abd El-Hay SS, El-Henawee MM, Eissa MS. Spectral analysis of severely overlapping spectra based on newly developed mathematical filtration techniques and ratio spectra manipulations: An application to the concurrent determination of dapoxetine and sildenafil in combined dosage form. Spectrochim Acta A Mol Biomol Spectrosc. 2021 Jul 5;255:119715. doi: 10.1016/j.saa.2021.119715. Epub 2021 Mar 19. PMID: 33799188.
   https://www.sciencedirect.com/science/article/abs/pii/S1386142521002912?via%3Dihub
3. dysfunction: a systematic review and meta-analysis. Arch Intern Med. 2002 Jun 24;162(12):1349-60. doi: 10.1001/archinte.162.12.1349. PMID: 12076233. https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/211714
4. Loran OB, Ströberg P, Lee SW, Park NC, Kim SW, Tseng LJ, Collins S, Stecher VJ. Sildenafil citrate 100 mg starting dose in men with erectile dysfunction in an international, double-blind, placebo-controlled study: effect on the sexual experience and reducing feelings of anxiety about the next intercourse attempt. J Sex Med. 2009 Oct;6(10):2826-35. doi: 10.1111/j.1743-6109.2009.01428.x. PMID: 19817982. https://www.jsm.jsexmed.org/article/S1743-6095(15)32273-6/fulltext
5. McMahon CG. Dapoxetine for premature ejaculation. Expert Opin Pharmacother. 2010 Jul;11(10):1741-52. doi: 10.1517/14656566.2010.493174. PMID: 20540653. https://www.tandfonline.com/doi/abs/10.1517/14656566.2010.493174?journalCode=ieop20
6. Martin-Tuite P, Shindel AW. Management Options for Premature Ejaculation and Delayed Ejaculation in Men. Sex Med Rev. 2020 Jul;8(3):473-485. doi: 10.1016/j.sxmr.2019.09.002. Epub 2019 Oct 23. PMID: 31668585. https://www.sciencedirect.com/science/article/abs/pii/S2050052119300952?via%3Dihub