Description
What Is Tadalista Professional 20mg?
Tadalista Professional 20mg is a sublingual tablet that contains tadalafil, a phosphodiesterase type 5 (PDE5) inhibitor. It is prescribed for the treatment of erectile dysfunction (ED), a condition in which a man is unable to achieve or maintain an erection sufficient for sexual activity. Tadalista Professional 20mg enhances blood flow to the corpus cavernosum of the penis during sexual stimulation, helping to initiate and maintain an erection.
What Is Tadalista Professional 20mg Used For?
Tadalista Professional 20mg is used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension. In the United States, tadalafil is marketed as Cialis for ED and BPH, and as Adcirca for pulmonary arterial hypertension. Erectile dysfunction is defined as the inability to attain or sustain a penile erection sufficient for satisfactory sexual performance. Tadalafil is not a cure but provides symptomatic relief by improving blood flow.
For benign prostatic hyperplasia, tadalafil reduces symptoms such as urinary urgency, weak stream, and frequent urination. A meta-analysis confirms that tadalafil provides symptom relief comparable to tamsulosin with fewer adverse effects.
For pulmonary arterial hypertension, tadalafil improves exercise capacity by reducing pulmonary vascular resistance.
How Long Does It Take For Tadalista Professional 20mg To Start Working?
Tadalista Professional 20mg typically begins to work within 15 to 20 minutes after sublingual administration. Onset time may vary based on metabolic rate, food intake, and general health. Tadalafil is rapidly absorbed and acts by inhibiting the PDE5 enzyme.
The mechanism begins when sexual stimulation triggers nitric oxide (NO) release from penile nerve endings and endothelial cells. NO activates the enzyme guanylate cyclase, which increases cyclic guanosine monophosphate (cGMP) production. cGMP relaxes smooth muscle in the corpus cavernosum, allowing blood to flow into the penis and cause an erection.
PDE5 breaks down cGMP, limiting the duration of an erection. Tadalafil inhibits PDE5, preserving cGMP levels and prolonging muscle relaxation and penile engorgement. However, tadalafil requires sexual arousal to initiate this biochemical cascade. Without sexual stimulation, tadalafil has no effect.
Tadalafil has a half-life of approximately 17.5 hours, which is significantly longer than that of sildenafil or vardenafil. This contributes to its prolonged duration of action and makes it suitable for daily or intermittent use in various conditions.
How Long Do The Effects Of Tadalista Professional 20mg Last?
The effects of Tadalista Professional 20mg can last up to 36 hours. Duration may vary depending on age, overall health, and individual tolerance. Peak plasma concentrations are reached within two hours of dosing, and its extended half-life of 17.5 hours allows for a prolonged therapeutic window. Sexual stimulation is still required during this period for the drug to be effective.
What Is The Recommended Dosage Of Tadalista Professional 20mg?
The typical dosage of Tadalista Professional is 20mg taken once within a 24-hour period, approximately 15 to 20 minutes before planned sexual activity. This dose should not be exceeded. Always follow your healthcare provider’s recommendations, as individual adjustments may be required based on response and tolerability.
How to Take Tadalista Professional 20mg 100mg Tablets for the Best Results?
Swallow the tablet whole with water. Tadalista Professional 20mg may be taken with or without food. For faster results, it is best taken on an empty stomach. Avoid heavy or fatty meals before consumption, as they can delay the drug’s absorption and reduce efficacy. Take it at least one hour before intended sexual activity to ensure optimal performance.
What Are The Side Effects Of Tadalista Professional 20mg Tablet?
Tadalista Professional 20mg may cause side effects. Most are mild or moderate and diminish over time.
Common Side Effects:
- Headache
- Muscle pain
- Flushing
- Indigestion
- Nasal congestion
- Back pain
- Dizziness
Less Common Side Effects
- Hypertension or hypotension
- Vision changes (blurred vision or blue-tinted vision)
- Gastrointestinal issues (diarrhea, constipation)
- Fatigue
- Urinary tract infections
- Respiratory infections
Rare Side Effects:
- Priapism (prolonged erection >4 hours)
- Sudden hearing loss
- NAION-related vision loss (non-arteritic anterior ischemic optic neuropathy)
Seek immediate medical attention if any serious or persistent effects occur.
What Are The Drug Interactions Of Tadalista Professional 20mg?
Tadalista Professional 20mg can interact with medications that affect blood pressure or liver enzymes. The table below outlines potential drug interactions.
| Drug Class or Substance | Interaction Effect |
|---|---|
| Nitrates (e.g., nitroglycerin) | Severe hypotension; contraindicated |
| Alpha-blockers (e.g., tamsulosin) | Additive hypotensive effects |
| Antihypertensives (e.g., amlodipine, enalapril) | Mild blood pressure reduction |
| Alcohol | Enhanced vasodilation, dizziness, hypotension |
| CYP3A4 Inhibitors (e.g., ketoconazole, ritonavir) | Increased tadalafil exposure, risk of toxicity |
| CYP3A4 Inducers (e.g., rifampin, phenytoin) | Decreased tadalafil effectiveness |
| Antacids (e.g., magnesium hydroxide) | Slower absorption, unchanged total exposure |
| CYP Substrates (e.g., theophylline, warfarin) | No significant pharmacokinetic change |
Can I Take Tadalista Professional 20mg With Food Or Alcohol?
Tadalista Professional 20mg can be taken with or without food. However, consuming a high-fat meal may delay its onset. Alcohol should be avoided or used in moderation. Large quantities of alcohol can reduce drug efficacy and increase the risk of side effects such as dizziness, headache, and low blood pressure.
How Should Tadalista Professional 20mg Be Stored?
Follow the storage instructions listed below to ensure the maximum potency of your drug.
- Keep in a cool, dry place below 30°C (86°F)
- Store away from direct sunlight
- Keep out of reach of children and pets
- Do not store in bathroom cabinets (due to humidity)
- Use only until the expiry date
- Keep in the original blister packaging
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