Description
What Is Tadarise 60mg?
Tadarise 60 mg is an oral medication that contains the active ingredient tadalafil. Tadalafil is a selective phosphodiesterase type 5 (PDE5) inhibitor. This medicine is prescribed to treat erectile dysfunction (ED), a condition marked by the inability to achieve or maintain an erection sufficient for sexual activity. Tadarise 60 mg increases blood flow to the corpus cavernosum of the penis during sexual arousal, which helps initiate and sustain an erection.
What Is Tadarise 60mg Used For?
Tadarise 60 mg is used to treat erectile dysfunction, benign prostatic hyperplasia (BPH), and pulmonary arterial hypertension (PAH). Erectile dysfunction is defined as the consistent or recurrent inability to attain and maintain a penile erection adequate for satisfactory sexual performance. While Tadarise 60 mg is not a cure for ED, it improves erectile response during sexual stimulation. In the United States, tadalafil is approved as Cialis for ED and BPH and as Adcirca for PAH.
Tadalafil is effective in relieving lower urinary tract symptoms due to BPH, such as urgency, hesitancy, and weak urine stream.
How Long Does It Take For Tadarise 60mg To Start Working?
Tadarise 60 mg usually begins to work within 30 to 60 minutes after oral administration. The onset may vary depending on individual metabolism, food intake, and general health. The pharmacological mechanism involves inhibition of PDE5, an enzyme that breaks down cyclic guanosine monophosphate (cGMP). During sexual stimulation, nitric oxide (NO) is released in the corpus cavernosum. This stimulates the synthesis of cGMP, which relaxes smooth muscle and increases blood flow to the penis.
By inhibiting PDE5, tadalafil prolongs the action of cGMP. This leads to enhanced vasodilation and increased penile blood flow. However, tadalafil requires sexual stimulation to be effective. It does not produce an erection in the absence of arousal. Among PDE5 inhibitors, tadalafil has the longest half-life of 17.5 hours, contributing to its extended duration of action. This longer half-life also supports its use in once-daily dosing for conditions like ED.
How Long Do The Effects Of Tadarise 60mg Last?
The effects of Tadarise 60 mg can last up to 36 hours in healthy adult males. The exact duration depends on age, health status, metabolic rate, and tolerance to the medication. Tadalafil reaches peak plasma concentration approximately 2 hours after dosing. Its long half-life of 17.5 hours allows for a sustained therapeutic effect, making it suitable for prolonged erectile responsiveness. However, sexual stimulation is still necessary for the drug to be effective at any point within this window.
What Is The Recommended Dosage Of Tadarise 60mg?
The recommended dose of Tadarise 60 mg is one tablet taken once within a 24-hour period. It should be taken approximately 30 minutes to one hour before anticipated sexual activity. Patients should not exceed one dose per day. Dosage adjustments may be required for individuals with renal or hepatic impairment, and only a qualified healthcare provider should make such changes.
How to Take Tadarise 60mg 100mg Tablets for the Best Results?
Swallow Tadarise 60 mg whole with water. It can be taken with or without food, but consuming it on an empty stomach may result in faster onset. Avoid taking the tablet after a high-fat meal, as it may delay absorption. For optimal results, take the tablet about one hour before planned sexual activity. Do not crush, chew, or split the tablet.
What Are The Side Effects Of Tadarise 60mg Tablet?
Tadarise 60 mg may cause side effects. Most are mild to moderate and often resolve as the body adjusts to the medication.
Common Side Effects
- Headache
- Indigestion
- Flushing
- Back pain
- Muscle aches
- Nasal congestion
Less Common Side Effects
- Dizziness
- Diarrhea or constipation
- Visual disturbances
- Urinary tract infections
Rare Side Effects
- Prolonged erection (priapism)
- Sudden vision loss (linked to NAION)
- Sudden hearing loss
- Hypotension
- Allergic reactions
Seek immediate medical attention if any severe or rare side effects occur. Do not take Tadarise with nitrate-based medications due to the risk of dangerous blood pressure drops.
What Are The Drug Interactions Of Tadarise 60mg?
Tadarise 60 mg may interact with other medications that affect cardiovascular function, blood pressure, or liver enzymes. The following table outlines known interactions:
| Interacting Agent | Interaction |
|---|---|
| Nitrates (e.g. nitroglycerin) | Contraindicated; may cause severe hypotension |
| Alpha-blockers (e.g. tamsulosin) | May cause additive blood pressure lowering |
| Antihypertensives (e.g. enalapril) | May increase hypotensive effects |
| Alcohol | Increases risk of dizziness and blood pressure drop |
| CYP3A4 inhibitors (e.g. ketoconazole, ritonavir) | Increases tadalafil levels, enhancing effects and side effects |
| CYP3A4 inducers (e.g. rifampin) | Decreases tadalafil levels, reducing effectiveness |
| Antacids | Delays absorption, no impact on overall exposure |
| P-glycoprotein substrates (e.g. digoxin) | No significant interaction found |
Can I Take Tadarise 60mg With Food Or Alcohol?
Tadarise 60 mg can be taken with or without food. However, a high-fat meal may delay its onset of action. Alcohol can reduce the effectiveness of the medication and increase the risk of side effects such as dizziness, low blood pressure, and headache. For best results, limit or avoid alcohol consumption while taking Tadarise.
How Should Tadarise 60mg Be Stored?
Follow the storage instructions listed below to ensure the maximum potency of your drug.
- Keep in a cool, dry place below 30°C (86°F)
- Store away from direct sunlight
- Keep out of reach of children and pets
- Do not store in bathroom cabinets (due to humidity)
- Use only until the expiry date
- Keep in the original blister packaging
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