Vidalista 40 mg

Vidalista 40mg is a medication that helps improve erectile function. It contains a high dose of the active ingredient tadalafil. During sexual stimulation, tadalafil improves blood flow to the penis. This improves the ability to get or keep an erection hard enough for sexual intercourse. This makes it effective at treating erectile dysfunction (ED). Vidalista also helps manage benign prostatic hyperplasia and pulmonary arterial hypertension. Centurion Laboratories Pvt. Ltd. is the manufacturer of this drug.

How does it Work?

Vidalista 40mg contains the active ingredient tadalafil. It belongs to a group of drugs called PDE5 inhibitors.

When a person is sexually stimulated, a molecule called nitric oxide (NO) is released within the penis. This increases levels of another molecule called the cGMP. cGMP causes the smooth muscles inside the penis to relax.

As a result, the blood vessels open wider allowing for blood to flow. It causes the corpus cavernosa (the spongy tissue in the penis responsible for erections) to swell. Thus, the penis becomes larger and stiff enough for sexual intercourse.

However, an enzyme called PDE5 breaks down cGMP molecules, ending the erection. PDE5 inhibitors such as tadalafil stop PDE5 from working too fast. It prevents the cGMP breakdown. Hence, the action of nitric oxide is enhanced, promoting blood flow. This helps prolong the erection, making it firm enough for intercourse.

Note that Vidalista itself does not directly cause an erection. It helps the body respond better to sexual arousal. A person needs to be sexually stimulated for the medicine to work.

Tadalafil lasts longer than PDE5 inhibitors such as sildenafil. Sildenafil (e.g., Viagra) remains in effect for 4 to 6 hours. Tadalafil (Vidalista) helps improve erections for up to 36 hours.

Uses

• Erectile Dysfunction (ED):

Difficulty getting or keeping an erection suitable for sex.

• Benign Prostatic Hyperplasia (BPH):

A benign condition in which the prostate gland is larger than usual. Men with this BPH may have problems with urination. Benign means it’s not cancer.

• Pulmonary Arterial Hypertension (PAH):

A type of high blood pressure that affects the lungs.

Recommended Dose

The recommended dosage of Vidalista 40mg is a tablet once a day. If you take it as required for ED, take it 30 minutes to 1 hour before sex. Take the tablet as a whole; swallow it with a glass of water. You can take it with or without food.

Do not take 2 doses of generic Vidalista at the same time. Do not take an extra dose or more than one tablet in 24 hours.

For treating other conditions, take Vidalista as prescribed. Doses can vary as per your response to the medicine. Ask your doctor how often and how much you should take it.

Missed Dose

For erectile dysfunction, Vidalista 40mg is taken when needed. So, there is little chance of missing a dose. If you’re not sure if you took a pill or skipped a dose by mistake, leave it out for the day. Keep a gap of at least 24 hours between doses.

For BPH or PAH, if you miss a dose, take it as soon as you remember. If you remember at a time close to your next dose, skip the missed dose. Continue the next doses as usual.

Overdose

Like any medication, tadalafil can cause harm when taken too much. The medication is meant to have an effect on blood pressure. Taking too much may pose serious risks to your circulation and whole body. Do not take extra doses to get faster results. If an overdose occurs, seek medical help right away.

Side Effects

The most commonly reported side effects of Vidalista 40mg are:

• headache
• indigestion
• heartburn
• nausea
• diarrhea
• flushing (a sudden hot, uneasy feeling in the skin)
• pain in the stomach, muscles, back, arms, or legs
• cough

In rare cases, more serious side effects can occur including:

• loss of vision
• blurred vision
• changes in color vision
• loss of hearing
• ringing in ears
• painful erection that lasts longer than 4 hours
• dizziness
• chest pain

Safety Advice

• Take Vidalista 40mg as directed by your physician.
• Do not take this medicine if you are allergic to tadalafil.
• Do not take Vidalista 40mg while taking certain medicines. Ask your doctor about any possible drug interactions.
• Read the label. Check all information before starting with the medicine.
• Discuss with a doctor if you wish to take it on a regular basis. They should know your full medical history e.g., if you had:
  • heart disease
  • stroke
  • low blood pressure
  • liver or kidney problems
  • bleeding disorders
  • any other health conditions
• Vidalista may make you feel dizzy or affect your vision. Do not drive or operate heavy machinery while taking it.
• Alcohol itself can make it more difficult to get an erection. It may change how well your medicine works and cause side effects. Avoid having large amounts of alcohol If you’re taking it for ED.
• Do not have it with grapefruit juice. Grapefruit juice can interact with medicines.
• Vidalista 40mg is not approved to be used by women or children.
• If you see any side effects, and they get worse over time, seek emergency care.

Medical Interactions

Certain medications do not work well together with Vidalista 40mg. Know your medicines and use caution to avoid drug interactions. Inform your doctor about all medicines and supplements you are taking. This may include:

• prescription drugs
• over-the-counter (OTC) medications
• vitamins
• herbs
• any other supplement

Vidalista 40mg can interact with:

• nitrates or diltiazem (used to treat patients with angina)
• alpha-blockers (i.e., those given for hypertension)
• some antifungals such as fluconazole
• aprepitant (helps with nausea and vomiting);
• bosentan (or other medications for high blood pressure);
• carbamazepine (relieves nerve pain);
• antibiotic such as clarithromycin, erythromycin
• efavirenz (treats and prevents HIV/AIDS);
• HIV protease inhibitors
• other medications for erectile dysfunction
• other medications for PAH
• anxiety-relieving medicines such as phenobarbital
• antidepressant drugs such as sertraline

This is not an exhaustive list, but it shows possible drug interactions. When in doubt, ask a pharmacist or doctor.

Storage

• Vidalista 40mg should be stored at room temperature.
• Keep the tablets in their original packaging. Do not mix with other medicines.
• Store it in a dark, dry place, away from the bathroom or sink. Excessive heat, air, light, and moisture can damage the pills.
• Keep it out of children’s or pet’s reach.
• Read the label first before you use a medicine. Check the expiry date printed on the label. Discard old, expired medicines or those no longer needed. Use your local waste disposal guidelines to dispose of them. Do not flush the pills down the toilet.

FAQs

 

1. What is Vidalista 40mg?

   Vidalista 40mg is a medication used to treat erectile dysfunction (ED) in men. It contains tadalafil as its active ingredient. It belongs to a class of drugs called PDE5 inhibitors.

2. How does Vidalista 40mg work?

   Tadalafil is the active ingredient in Vidalista 40mg. It works by blocking the action of the enzyme called PDE5. By blocking PDE5, it allows the blood vessels in the penis to relax. This increases blood flow to the penis during sexual stimulation. The improved blood flow helps men achieve and maintain an erection.

3. How do I take Vidalista 40mg?

   Vidalista 40mg should be taken orally. Take a single dose as a whole with a glass of water. You may take it 30 minutes before sexual activity. It can be taken with or without food. However, consuming alcohol may make it less effective. Do not combine Vidalista and large amounts of alcohol. It may lead to unwanted effects and can make you sick.

4. How long does Vidalista 40mg last?

   The effects of this medicine can last for up to 36 hours. Much longer than other ED medications like Viagra. This long duration of action makes tadalafil popular as the “weekend pill.”

Refrences

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2. Hatzimouratidis K. A review of the use of tadalafil in the treatment of benign prostatic hyperplasia in men with and without erectile dysfunction. Ther Adv Urol. 2014 Aug;6(4):135-47. doi: 10.1177/1756287214531639. PMID: 25083163; PMCID: PMC4054509. https://journals.sagepub.com/doi/10.1177/1756287214531639
3. Gong B, Ma M, Xie W, Yang X, Huang Y, Sun T, Luo Y, Huang J. Direct comparison of tadalafil with sildenafil for the treatment of erectile dysfunction: a systematic review and meta-analysis. Int Urol Nephrol. 2017 Oct;49(10):1731-1740. doi: 10.1007/s11255-017-1644-5. Epub 2017 Jul 24. PMID: 28741090; PMCID: PMC5603624.https://link.springer.com/article/10.1007/s11255-017-1644-5
4. Frajese GV, Pozzi F, Frajese G. Tadalafil in the treatment of erectile dysfunction; an overview of the clinical evidence. Clin Interv Aging. 2006;1(4):439-49. doi: 10.2147/ciia.2006.1.4.439. PMID: 18046921; PMCID: PMC2699638. https://www.atypon-link.com/DMP/doi/abs/10.2147/ciia.2006.1.4.439
5. Wang Y, Bao Y, Liu J, Duan L, Cui Y. Tadalafil 5 mg Once Daily Improves Lower Urinary Tract Symptoms and Erectile Dysfunction: A Systematic Review and Meta-analysis. Low Urin Tract Symptoms. 2018 Jan;10(1):84-92. doi: 10.1111/luts.12144. Epub 2016 Nov 5. PMID: 29341503 https://onlinelibrary.wiley.com/doi/10.1111/luts.12144
6. Sofikitis N, Kaltsas A, Dimitriadis F, Rassweiler J, Grivas N, Zachariou A, Kaponis A, Tsounapi P, Paterakis N, Karagiannis A, Skouros S, Giannakis I, Champilomatis I, Paschopoulos M, Daphnis D, Giakoumakis I, R Gabales M, M Chua JB, Lantin Iii PL, Mamoulakis C, Takenaka A. The Effect of PDE5 Inhibitors on the Male Reproductive Tract. Curr Pharm Des. 2021;27(23):2697-2713. doi: 10.2174/1381612826666200226121510. PMID: 32101115.                                                  https://www.eurekaselect.com/article/104866