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Vidalista Professional 20mg is a sublingual tablet manufactured by Centurion Laboratories for the treatment of erectile dysfunction. It contains 20mg of tadalafil, a phosphodiesterase type 5 (PDE5) inhibitor that increases blood flow to the penis during sexual stimulation. As a generic version of Cialis, it is not intended for women or children. The tablet typically starts working within 15 to 20 minutes and remains effective for up to 36 hours, making it known as the “weekend pill.” Each blister pack contains 10 sublingual tablets. This prescription medication should be used under medical supervision.
Vidalista Professional 20mg is a prescription medication used to treat erectile dysfunction. It contains tadalafil as the active pharmaceutical ingredient. Tadalafil is a selective inhibitor of phosphodiesterase type 5 (PDE5), an enzyme responsible for the breakdown of cyclic guanosine monophosphate (cGMP) in the corpus cavernosum of the penis. By inhibiting PDE5, Vidalista Professional enhances erectile function by sustaining elevated levels of cGMP, allowing increased blood flow to the penis during sexual arousal. This medication is not effective in the absence of sexual stimulation.
Vidalista Professional 20mg is indicated for the treatment of erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension. Erectile dysfunction is defined as the consistent inability to achieve or maintain an erection sufficient for satisfactory sexual performance. Tadalafil, the active component, does not cure erectile dysfunction but supports the physiological process necessary for an erection in response to sexual stimulation.
In cases of benign prostatic hyperplasia, tadalafil helps relieve symptoms such as urinary urgency, weak stream, and frequent urination. It has demonstrated similar efficacy to tamsulosin with a low incidence of adverse effects. Tadalafil is also FDA-approved under the brand name Adcirca for improving exercise capacity in individuals with pulmonary arterial hypertension by relaxing blood vessels in the lungs and lowering pulmonary artery pressure.
Vidalista Professional 20mg generally begins to work within 15 to 20 minutes after sublingual administration. The onset may vary depending on individual metabolism, food intake, and overall health status.
Tadalafil, a PDE5 inhibitor, works by enhancing the natural erectile response to sexual stimulation. Sexual arousal triggers the release of nitric oxide (NO) from nerve endings and endothelial cells in the penis. NO activates the enzyme guanylate cyclase, which catalyzes the formation of cGMP. This molecule promotes relaxation of smooth muscle in the corpus cavernosum and dilation of penile arteries, leading to increased blood flow and erection.
PDE5 normally degrades cGMP, terminating the erection. Tadalafil inhibits PDE5, prolonging the action of cGMP and sustaining erection duration. Its distinguishing feature is a longer half-life of approximately 17.5 hours, compared to sildenafil and vardenafil which have shorter half-lives of 4–5 hours. This extended duration contributes to the drug’s effectiveness over a 36-hour window, earning it the nickname “the weekend pill.” However, the pharmacological action is only triggered by sexual stimulation, as tadalafil does not initiate erection in the absence of arousal.
The effects of Vidalista Professional 20mg typically last up to 36 hours. This prolonged action is attributed to tadalafil’s terminal half-life of approximately 17.5 hours. Peak plasma concentrations are usually achieved within 2 hours after administration. However, onset and duration can vary based on age, metabolic rate, diet, and comorbid health conditions.
While the drug remains pharmacologically active in the body for more than a day, it does not cause continuous erections. The medication facilitates erectile function only when sexual stimulation occurs. This extended duration provides greater flexibility in sexual activity, allowing for more spontaneous encounters during the effective period.
The recommended dosage of Vidalista Professional 20mg is one tablet per 24-hour period, typically taken 30 to 60 minutes before anticipated sexual activity. Patients should not exceed one dose within a 24-hour timeframe. Dosage adjustments must be guided by a qualified healthcare professional, especially in patients with hepatic or renal impairment. Tadalafil exhibits dose-dependent pharmacokinetics and should be administered based on individual tolerability and therapeutic response.
Vidalista Professional 20mg should be taken by placing the sublingual tablet under the tongue and allowing it to dissolve completely. It can be taken with or without food, although ingestion on an empty stomach may result in a quicker onset of action. Consumption following a high-fat meal may delay absorption and reduce peak plasma concentrations. Alcohol should be limited, as it can impair the drug’s effectiveness and exacerbate side effects such as dizziness or hypotension. The tablet should be used approximately 1 hour before planned sexual activity for best results.
Tadalafil-based tablets may cause side effects, most of which are mild and self-limiting.
Common Side Effects:
Less Common Side Effects:
Rare Side Effects:
Patients should seek immediate medical attention if they experience symptoms of priapism, vision changes, or hearing loss. The use of tadalafil in individuals taking nitrate-containing medications is contraindicated due to the risk of severe hypotension.
Vidalista Professional 20mg may interact with several medications and substances, especially those affecting blood pressure and liver metabolism.
Drug Category | Interaction Details |
---|---|
Nitrates | Contraindicated. Severe hypotension may occur. At least 48 hours should elapse before co-administration. |
Alpha-blockers | May cause additive blood pressure-lowering effects. Caution is advised. |
Antihypertensives | May mildly enhance the blood pressure-lowering effects of medications like enalapril and amlodipine. |
Alcohol | May increase risk of dizziness and hypotension. Avoid substantial consumption. |
Antacids | May delay absorption without affecting total drug exposure. |
CYP3A4 Inhibitors | (e.g., ketoconazole, ritonavir) Increase tadalafil exposure. Dose adjustment may be necessary. |
CYP3A4 Inducers | (e.g., rifampin, carbamazepine) Reduce tadalafil exposure and potentially decrease efficacy. |
Other CYP Substrates | No clinically significant effect (e.g., warfarin, midazolam, theophylline). |
Vidalista Professional 20mg can be taken with or without food, although consuming it on an empty stomach may improve onset speed. A high-fat meal may delay the absorption of tadalafil, resulting in reduced efficacy. Alcohol acts as a vasodilator and may increase the risk of side effects such as dizziness, hypotension, and flushing. For best results and to minimize side effects, avoid or limit alcohol intake while using this medication.
Follow these storage instructions to maintain the quality and effectiveness of Vidalista Professional 20mg:
Published on: June 2, 2025
Last Modified on: July 8, 2025
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