Silagra 100 mg Tablet

What Is Silagra 100 Mg?

Silagra 100 mg is a PDE5 inhibitor prescribed to treat erectile dysfunction in men. The active ingredient in Silagra 100 mg is sildenafil citrate. This compound inhibits the PDE5 enzyme, which regulates blood flow in the penis. When taken before sexual activity, Silagra 100 enhances blood circulation to the corpus cavernosum, the erectile tissue of the penis. This leads to a sustained erection during sexual stimulation. Silagra does not increase libido or cause an erection without arousal. It is a generic medication equivalent to Viagra, approved for adult males with ED.

What Is Silagra 100 Mg Used For?

Silagra 100 mg is used to manage erectile dysfunction in adult men. Erectile dysfunction (ED) is the consistent inability to get or keep an erection firm enough for sexual intercourse. Silagra 100 mg helps by increasing blood flow to the penis in response to sexual stimulation. It supports normal erectile function but does not cure ED or address its underlying causes. The medication works only when a man is sexually aroused and has a functioning nitric oxide pathway.

How Long Does It Take For Silagra 100 Mg To Start Working?

Silagra 100 mg starts working within 30 to 60 minutes after oral intake. The onset time depends on individual metabolism, recent food intake, and overall health. For best results, it should be taken on an empty stomach. Sildenafil, the active agent in Silagra, blocks the PDE5 enzyme in the smooth muscle cells of the corpus cavernosum. Normally, sexual arousal causes the release of nitric oxide (NO), which activates guanylate cyclase enzymes. This increases levels of cyclic guanosine monophosphate (cGMP), leading to smooth muscle relaxation.

PDE5 degrades cGMP. Silagra inhibits PDE5, allowing cGMP levels to remain elevated. This prolongs the dilation of blood vessels in the penis and supports an erection. The molecular structure of sildenafil is similar to cGMP, which lets it bind competitively to the PDE5 receptor. As a result, more blood enters the erectile tissue. Without sexual stimulation, this pathway is inactive, and the medication has no effect.

Sildenafil is metabolized in the liver, primarily by CYP3A4 and CYP2C9 enzymes. Its major metabolite, N-desmethylated sildenafil, retains about 40% of the parent compound’s PDE5-inhibitory activity and contributes to the drug’s overall effect. Silagra’s absorption can be delayed by high-fat meals. It reaches peak plasma concentration in about 1 hour and is excreted mostly via feces and urine.

How Long Do The Effects Of Silagra 100 Mg Last?

The effects of Silagra 100 mg last for about 4 to 6 hours. This window varies based on individual age, health, and dosage tolerance. Sexual stimulation is still required during this period for an erection to occur. Silagra has a terminal half-life of around 3 to 5 hours. Peak plasma levels are achieved in about 60 minutes. While the drug’s presence in the bloodstream declines after a few hours, its functional effects can persist during the active window. The duration of effect may decrease in older adults or those with metabolic disorders.

What Is The Recommended Dosage Of Silagra 100 Mg?

The standard dose is one 100 mg tablet taken once per 24-hour period. Silagra 100 mg should be taken about 30 to 60 minutes before sexual activity. Patients should not exceed one dose in a 24-hour period. Those with liver or kidney impairment may require a lower starting dose. Dosage adjustments must be guided by a healthcare provider. Do not split or crush the tablet.

How to Take Silagra 100 Mg 100mg Tablets for the Best Results?

Silagra 100 mg should be swallowed whole with water, preferably on an empty stomach.

Food does not affect the medication’s mechanism, but fatty meals can delay absorption and reduce peak plasma concentration. For best results, take Silagra about one hour before planned sexual activity. Do not take the tablet with grapefruit or alcohol, as both can interfere with drug metabolism and potency.

What Are The Side Effects Of Silagra 100 Mg Tablet?

Silagra 100 mg may cause mild to moderate side effects that often resolve as the body adapts.

Common Side Effects

• Headache
• Flushing (warmth or redness of the face)
• Nasal congestion
• Indigestion
• Dizziness

Less Common Side Effects

• Blurred vision
• Muscle pain
• Rash
• Diarrhea
• Sensitivity to light

Rare Side Effects

• Sudden hearing loss
• Priapism (prolonged or painful erection lasting over 4 hours)
• Severe hypotension
• Vision loss in one or both eyes (NAION)
• Allergic reaction (swelling of the face, lips, or throat)

Seek immediate medical help if any rare or severe effects occur.

What Are The Drug Interactions Of Silagra 100 Mg?

Silagra 100 mg can interact with medications that affect blood pressure, liver enzymes, or sexual function.

Can I Take Silagra 100 Mg With Food Or Alcohol?

Silagra 100 mg can be taken with or without food, but fatty meals may delay its effect.

A high-fat meal can reduce sildenafil absorption and delay its onset of action by about an hour. Alcohol may reduce the effectiveness of Silagra and increase side effects such as dizziness or low blood pressure. To optimise results, limit alcohol intake or avoid it entirely while using this medication.

How Should Silagra 100 Mg Be Stored?

Store Silagra 100 mg properly to maintain its stability and potency.

• Keep in a cool, dry place below 30°C (86°F)
• Store away from direct sunlight
• Keep out of reach of children and pets
• Do not store in bathroom cabinets (due to humidity)
• Use only until the expiry date
• Keep in the original blister packaging

Written & Reviewed By

Dr. William Henderson

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