How does it Work?
The medication contains the active ingredient Sildenafil Citrate. This ingredient enhances blood flow to the penis during sexual arousal. The improved blood flow facilitates an erection.
During sexual stimulation, the blood vessel lining in the penis releases nitric oxide (NO), which triggers the production of cGMP in the smooth muscle cells of the penis.
cGMP prompts the smooth muscle cells to relax. This action widens the penis’ blood vessels.
The relaxation of smooth muscle cells allows for improved blood flow into the spongy tissue of the penis. This tissue is called the corpus cavernosum.
The increased blood flow fills the spongy tissue, leading to an erection.
These pills do not directly induce an erection. Instead, it enhances the natural erectile response by amplifying penile blood flow upon sexual stimulation.
Uses
- Erectile dysfunction (ED): A condition characterized by the inability to achieve and maintain an erection.
- Pulmonary arterial hypertension (PAH): A condition characterized by high blood pressure in the arteries that carry blood from the heart to the lungs.
Recommended Dose
The recommended starting dose of Silagra is 50mg, taken approximately 30-60 minutes before sexual activity.
The dose can be increased to 100mg or decreased to 25mg, depending on your response and tolerability.
Silagra can be taken with or without food. However, if taken after a high-fat meal, such as a cheeseburger and fries, it may take longer to start working.
Do not take the medication more than once a day.
Missed Dose
If you forget to take a dose, take it as soon as you remember. Do not take two doses at once to make up for the missed one.
If it’s nearly time for your next scheduled dose, skip the missed one and stick to your regular dosing routine. Avoid doubling up doses to make up for a missed one.
Overdose
Taking more than the recommended dose of Silagra can increase the risk of side effects and should be avoided.
Seek medical attention immediately if you experience symptoms of an overdose, such as severe dizziness, fainting, or prolonged and painful erection.
Side Effects
- Priapism:
An erection lasting more than 4 hours. Seek immediate medical help as priapism can damage the penis permanently.
- Sudden Vision Loss:
In one or both eyes, which could be a sign of a serious eye problem called Non-Arteritic Anterior Ischemic Optic Neuropathy (Naion).
- Sudden Hearing Decrease or Loss:
It is ccompanied by ringing in the ears (tinnitus) or dizziness.
Common Side Effects:
- Headache
- Flushing
- Upset stomach
- Changes in color vision (e.g., blue color tinge) and blurred vision
- Stuffy or runny nose
- Back pain
- Muscle pain
- Nausea
- Dizziness
- Rash
Rare Side Effects (Reported in Some Men):
- Heart attack
- Stroke
- Irregular heartbeats
- Death
If you experience any severe or persistent side effects or notice any changes in your health, consult your doctor immediately.
Safety Advice
Before Taking Silagra, inform your doctor if You:
- Allergic to sildenafil.
- Have or had stomach ulcers.
- Encounter liver problems.
- Have experienced heart problems like a heart attack, irregular heartbeat, angina (chest pain), aortic valve narrowing, or heart failure.
- Encounter blood cell issues such as sickle cell anemia, multiple myeloma, or leukemia.
- Previously had a stroke.
- Experience low blood pressure, or uncontrolled high blood pressure.
- Have a penis with an unusual shape.
- Previously had a prolonged erection lasting more than 4 hours.
- Underwent heart surgery in the past 6 months.
- Have pulmonary hypertension.
- Have been diagnosed with retinitis pigmentosa, a rare genetic eye disease.
- Experience bleeding problems.
- Have kidney problems or are undergoing kidney dialysis.
- Suffered severe vision loss or a condition called non-arteritic anterior ischemic optic neuropathy (NAION).
- Have any other existing medical conditions.
Silagra should only be taken under the supervision of a healthcare provider and should not be used by women or children.
Medical Interactions
Inform your doctor about all the medications you are currently taking. Silagra may interact with other drugs, leading to side effects. Especially mention if you take any of the following:
- Nitrates
- Guanylate Cyclase Stimulators such as riociguat (Adempas).
- Alpha Blockers like Hytrin, Flomax, Cardura, Minipress, Uroxatral, Jalyn, or Rapaflo. These are prescribed for prostate problems or high blood pressure.
- HIV Protease Inhibitors such as ritonavir (Norvir), indinavir sulfate (Crixivan), saquinavir (Fortovase or Invirase), or atazanavir sulfate (Reyataz).
- Oral Antifungal Medicines like ketoconazole (Nizoral) and itraconazole (Sporanox).
- Certain Antibiotics: Such as clarithromycin (Biaxin), telithromycin (Ketek), or erythromycin.
- Other Blood Pressure Medications
- Other Erectile Dysfunction (ED) Treatments
Silagra contains sildenafil, the same active ingredient found in REVATIO. REVATIO is a medication used for treating pulmonary arterial hypertension (PAH).
Therefore, do not use SILAGRA with REVATIO or other PAH treatments containing sildenafil or any other PDE5 inhibitors like Adcirca (tadalafil).
Drinking alcohol can temporarily impair your ability to achieve an erection. To ensure you get the maximum benefit from your medicine, it’s advisable to avoid excessive alcohol consumption before taking this medication.
Storage
Store Silagra at room temperature, away from moisture and heat.
FAQs
-
What are the doses of Silagra?
Silagra is available in 50mg and 100mg tablets. The recommended dose is to take it about 1 hour before planned sexual activity.
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Is Silagra a Viagra?
Yes, Silagra is similar to Viagra. Both contain the active ingredient sildenafil, which treats erectile dysfunction. Silagra is a generic version of Viagra.
-
Is Silagra 100 safe?
Silagra 100mg Tablet is generally safe for treating erectile dysfunction. It should be taken as advised by a doctor, about 1 hour before sexual activity.
-
What is Silagra benefits?
Silagra is a phosphodiesterase type 5 (PDE 5) inhibitor. It treats erectile dysfunction by increasing blood flow to the penis. It helps men get or maintain an erection.
Refrences
- Fink HA, Mac Donald R, Rutks IR, Nelson DB, Wilt TJ. Sildenafil for male erectile dysfunction: a systematic review and meta-analysis. Arch Intern Med. 2002 Jun 24;162(12):1349-60. doi: 10.1001/archinte.162.12.1349. PMID: 12076233. https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/211714
- Loran OB, Ströberg P, Lee SW, Park NC, Kim SW, Tseng LJ, Collins S, Stecher VJ. Sildenafil citrate 100 mg starting dose in men with erectile dysfunction in an international, double-blind, placebo-controlled study: effect on the sexual experience and reducing feelings of anxiety about the next intercourse attempt. J Sex Med. 2009 Oct;6(10):2826-35. doi: 10.1111/j.1743-6109.2009.01428.x. PMID: 19817982. https://www.jsm.jsexmed.org/article/S1743-6095(15)32273-6/fulltext
- Smith BP, Babos M. Sildenafil. [Updated 2022 May 3]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK558978/
- Galiè N, Ghofrani HA, Torbicki A, Barst RJ, Rubin LJ, Badesch D, Fleming T, Parpia T, Burgess G, Branzi A, Grimminger F, Kurzyna M, Simonneau G; Sildenafil Use in Pulmonary Arterial Hypertension (SUPER) Study Group. Sildenafil citrate therapy for pulmonary arterial hypertension. N Engl J Med. 2005 Nov 17;353(20):2148-57. doi: 10.1056/NEJMoa050010. Erratum in: N Engl J Med. 2006 Jun 1;354(22):2400-1. PMID: 16291984. https://www.nejm.org/doi/full/10.1056/NEJMoa050010
- Sofikitis N, Kaltsas A, Dimitriadis F, Rassweiler J, Grivas N, Zachariou A, Kaponis A, Tsounapi P, Paterakis N, Karagiannis A, Skouros S, Giannakis I, Champilomatis I, Paschopoulos M, Daphnis D, Giakoumakis I, R Gabales M, M Chua JB, Lantin Iii PL, Mamoulakis C, Takenaka A. The Effect of PDE5 Inhibitors on the Male Reproductive Tract. Curr Pharm Des. 2021;27(23):2697-2713. doi: 10.2174/1381612826666200226121510. PMID: 32101115. https://www.eurekaselect.com/article/104866
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