Modalert 100 mg

What is Modalert 100 mg?

Modalert 100 mg is a modafinil-based wakefulness-promoting tablet manufactured by Sun Pharma and approved for treating sleep-related conditions such as narcolepsy, obstructive sleep apnea, and shift work disorder. Each tablet contains 100 mg of modafinil, which is a central nervous system stimulant and a generic version of Provigil. Modalert 100 mg supports cognitive performance and helps reduce excessive daytime sleepiness without creating a strong euphoric effect.

Modalert is taken orally and begins working within 2 to 4 hours after ingestion. Its effects last up to 12 hours, making it ideal for patients who need sustained mental clarity through work, school, or night shifts. Food may delay absorption slightly but does not affect the total effectiveness. It is not recommended for children or adolescents under 17.

Many healthy adults also use Modalert 100 mg off-label to improve focus, reaction time, and productivity. While clinical studies show only modest improvements in these areas, the low-to-moderate dose makes it a preferred option for those who want a balanced cognitive boost without excessive stimulation. Modalert 100 mg is most effective when used responsibly and under medical supervision.

What is the use of the Modalert 100 tablet?

Modalert 100 mg is used to manage excessive sleepiness caused by narcolepsy, obstructive sleep apnea (OSA), and shift work sleep disorder (SWSD). It is also prescribed off-label for fatigue-related neurological conditions and attention-related disorders. In narcolepsy, Modalert helps control sudden sleep attacks and supports daytime alertness by addressing the brain’s lack of hypocretin, a chemical crucial for staying awake. While it doesn’t cure the condition, it improves functioning and focus.

For people with obstructive sleep apnea, Modalert 100 mg is used when residual sleepiness persists despite the use of CPAP therapy. It helps patients stay awake and productive during the day. In shift work sleep disorder, Modalert improves alertness during night shifts or irregular working hours. It helps regulate sleep-wake cycles in people whose work schedules disrupt natural sleep patterns.

Doctors also use Modalert 100 mg off-label to manage fatigue in conditions like multiple sclerosis (MS), and to improve attention and alertness in people with ADHD or bipolar depression. It may also be taken by healthy users under medical guidance for enhanced productivity.

How does Modalert 100 mg work?

Modalert 100 mg works by increasing the availability of dopamine in the brain, which helps promote wakefulness, concentration, and motivation. Modafinil, the active ingredient, blocks dopamine transporters and prevents dopamine reabsorption into nerve cells. This increases dopamine levels in the brain’s synaptic spaces and improves alertness.

Although this action is similar to that of amphetamines, modafinil binds differently to the transporter, reducing the risk of euphoria or dependency. Modafinil does not directly target serotonin or norepinephrine transporters but may influence them indirectly through dopamine regulation. It may also stimulate the orexin (hypocretin) system, which supports the brain’s control over sleep-wake cycles.

After oral intake, Modalert 100 mg reaches peak blood levels in 2 to 3 hours. Food can slow down absorption slightly, but does not affect the total drug exposure. Around 60% of the drug binds to plasma proteins, and it is primarily metabolized in the liver. The effects last 10 to 12 hours, and less than 10% is eliminated unchanged in urine. Women may have higher blood concentrations than men due to slower metabolism and increased bioavailability.

How long does Modalert 100 mg last?

Modalert 100 mg typically provides 10 to 12 hours of sustained mental clarity and reduced fatigue. After ingestion, peak effects are usually felt within 2 to 4 hours. The drug has a half-life of about 12 to 15 hours, which supports a gradual decline in energy rather than a sudden crash. This makes it suitable for daily use in people who need moderate yet stable cognitive support throughout the day. The smoother release profile is ideal for people who want enhanced wakefulness without overstimulation.

What is the recommended dosage of Modalert 100 mg?

The usual recommended dose is one 100 mg tablet per day, taken orally. For narcolepsy and sleep apnea, the tablet is taken in the morning. For shift work sleep disorder, it should be taken about one hour before the work shift starts. It may be consumed with or without food. However, high-fat meals might delay how quickly the drug begins to work. While some patients may be prescribed a second 100 mg dose later in the day, the total daily dose should not exceed 400 mg. Dosage should always be determined by a healthcare provider based on individual needs.

What are the side effects of Modalert 100 mg?

Some of the common side effects of Modalert 100 mg are listed below.

• Headache
• Dizziness
• Dry mouth
• Nausea
• Diarrhea
• Anxiety
• Insomnia

Less common side effects

• Back pain
• Belching
• Decrease in appetite
• Diarrhea
• Difficulty having a bowel movement
• Dryness of the skin
• Flushing
• Heartburn
• Indigestion
• Muscle stiffness

If the side effects persist for more than a day, call your doctor immediately.

What are the interactions of Modalert 100 mg?

Drug interactions can alter how a drug works or increase the risk of side effects. It is important to understand which medications your drug can interact with to minimize the risks. Talk to your doctor about your medical history. Here’s a list of drugs that interact with Modalert 100mg.

Modafinil Interaction Table

How should Modalert 100 mg be stored?

Follow the storage instructions listed below to ensure the maximum potency of your drug.

• Store Modalert 100mg at room temperature.
• Do not leave the pills in warm or humid places. Avoid storing them in the bathroom cabinet or near a sink. Heat, air, and steam can spoil the medicine.
• Do not repack the medicine. Store it in the original packaging until you consume it.
• Place the medicines in a locked cabinet where children and pets cannot reach.
• Do not take medicines that have expired. Even if you have bought it recently, check the label. If you’ve taken expired pills by mistake, inform your doctor.
• Discard any pills that have gone past their expiry date. Follow your local regulations and laws for their safe disposal

Written & Reviewed By

Dr. William Henderson

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