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Modawake 200 mg is a prescription-strength tablet containing 200 mg of modafinil, a central nervous system stimulant used to promote wakefulness in people with sleep disorders. It is manufactured by HAB Pharmaceuticals in India and serves as a generic version of Provigil. Modawake is indicated for narcolepsy, sleep apnea, and shift work sleep disorder, all of which are associated with extreme daytime drowsiness and reduced alertness.
Treats
Narcolepsy, Shift Work Disorder, and Obstructive Sleep Apnea
Contains
Modafinil
Lasts
around 12 hours
The tablet is taken by mouth and typically reaches its peak effect within 2 to 4 hours. Its impact lasts up to 10 to 12 hours, helping users remain alert and mentally active through long workdays or night shifts. While food may slow the onset, it does not reduce the total effect of the drug. Modawake is approved for adult use and should be taken under medical guidance. It is not recommended for individuals under 17.
Modawake 200 mg is also used off-label by professionals, students, and others seeking to improve mental performance, concentration, and energy levels. Although cognitive enhancement results vary, the drug is favoured for its ability to reduce mental fatigue without strong euphoria or crash. It provides consistent support throughout the day when used responsibly and as prescribed.
Modawake 200 mg is a prescription-strength tablet used to improve wakefulness in people suffering from narcolepsy, sleep apnea, or shift work sleep disorder. It is manufactured by HAB Pharmaceuticals and contains 200 mg of modafinil, a generic equivalent of Provigil. In narcolepsy, Modawake reduces the frequency of daytime sleep attacks and supports cognitive functioning by boosting levels of dopamine, a key neurotransmitter in wake regulation.
In cases of obstructive sleep apnea, patients may continue to feel sleepy during the day even after using CPAP therapy. Modawake 200 mg is prescribed to treat this residual drowsiness, improving alertness and overall daytime performance. It is also effective for shift work sleep disorder, helping people who work nights or irregular hours stay alert during their active period.
Doctors may prescribe Modawake off-label to treat fatigue in multiple sclerosis or to improve focus and alertness in people with ADHD or bipolar disorder during low-energy episodes. Healthy individuals may also use it under medical supervision to stay alert and focused during long tasks or demanding schedules.
Modawake 200 mg enhances wakefulness by blocking dopamine transporters and increasing dopamine levels in the brain. This action keeps dopamine active in the synaptic space, promoting better focus, alertness, and cognitive endurance. The active ingredient, modafinil, binds differently than amphetamines, which helps reduce the chance of abuse or strong euphoric effects.
Although Modawake does not directly affect serotonin or norepinephrine pathways, increased dopamine may indirectly raise levels of these neurotransmitters in some brain regions. The drug may also enhance activity in the orexin system, which helps control the sleep-wake cycle and maintain consistent energy levels during the day.
After oral administration, peak blood concentration is reached within 2 to 3 hours. The presence of food may delay absorption slightly but does not change the overall effect. Approximately 60% of modafinil binds to blood proteins. The half-life ranges from 10 to 12 hours, making Modawake effective for extended periods. The liver handles most of the metabolism, and only a small percentage is excreted unchanged in urine. Women may have higher plasma concentrations of modafinil due to slower clearance rates.
Modawake 200 mg typically lasts 10 to 12 hours and offers consistent cognitive support and energy during that time. Users generally experience peak effects between 2 to 4 hours after taking the tablet. The drug’s half-life of approximately 12 to 15 hours ensures a smooth, extended effect with minimal crash. This makes Modawake suitable for long work shifts, overnight assignments, or study sessions requiring sustained mental alertness.
The standard dosage is one 200 mg tablet taken once daily. For narcolepsy and obstructive sleep apnea, the tablet should be taken in the morning. For shift work sleep disorder, it is best taken about one hour before the work shift starts. It can be taken with or without food, although a high-fat meal may delay the onset of action. The maximum daily dose should not exceed 400 mg. Doubling the dose rarely increases benefit and may raise the risk of side effects. All dosage changes should be made under the supervision of a healthcare provider.
Side effects of Modawake 200 mg include:
If any of the above-mentioned side effects persist for long, seek medical attention immediately.
Drug interactions can alter how a drug works or increase the risk of side effects. Understanding which medications your drug can interact with is important to minimize the risks. Talk to your doctor about your medical history. Here’s a list of drugs that interact with Modawake 200mg.
Drug Class / Substance | Examples | Interaction Type | Effect on Patient |
---|---|---|---|
Hormonal contraceptives | Birth control pills, patches, implants | CYP3A4 induction | Reduced contraceptive effectiveness; backup methods recommended |
Antidepressants | Sertraline, fluoxetine, amitriptyline | CYP inhibition/induction | Increased or decreased drug levels; risk of serotonin imbalance |
Antiepileptics | Phenytoin, carbamazepine, phenobarbital | Enzyme induction | Lower seizure control; monitoring required |
Antipsychotics / Anxiolytics | Clozapine, risperidone, lorazepam | Metabolism alteration | Reduced sedative or therapeutic effect |
Antifungals | Ketoconazole, itraconazole | Shared metabolism pathways | Potential toxicity or reduced antifungal action |
Blood thinners | Warfarin | CYP2C19 inhibition | Unpredictable INR changes; bleeding risk or clot formation |
Stimulants / Caffeine | Adderall, Ritalin, energy drinks | Synergistic stimulant effects | Anxiety, insomnia, palpitations |
Alcohol | Beer, wine, spirits | CNS unpredictability | Increased impairment; risk of mood swings, blackouts |
Over-the-counter sleep aids | Diphenhydramine, melatonin | Opposing pharmacological effects | Reduced effectiveness of both agents |
Herbal supplements | St. John’s Wort, valerian | Enzyme induction or sedation | Lower modafinil levels or increased drowsiness |
Follow the storage instructions listed below to ensure the maximum potency of your drug.
Published on: April 28, 2022
Last Modified on: May 17, 2025
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