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Tadalista Professional 20mg is a prescription medication formulated as a sublingual tablet that contains the active ingredient tadalafil. Manufactured by Fortune Healthcare Pvt Ltd, it is classified as a phosphodiesterase type 5 (PDE5) inhibitor. This drug is primarily used for the treatment of erectile dysfunction (ED) and is known for its rapid onset time of 15 to 20 minutes and prolonged effectiveness lasting up to 36 hours. Each tablet contains 20mg of tadalafil and comes in blister packs of 10 pills. Tadalista Professional is a generic version of Cialis, often referred to as the “weekend pill” due to its long-lasting effects. It is not intended for use in women or children.
Tadalista Professional 20mg is a sublingual tablet that contains tadalafil, a phosphodiesterase type 5 (PDE5) inhibitor. It is prescribed for the treatment of erectile dysfunction (ED), a condition in which a man is unable to achieve or maintain an erection sufficient for sexual activity. Tadalista Professional 20mg enhances blood flow to the corpus cavernosum of the penis during sexual stimulation, helping to initiate and maintain an erection.
Tadalista Professional 20mg is used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension. In the United States, tadalafil is marketed as Cialis for ED and BPH, and as Adcirca for pulmonary arterial hypertension. Erectile dysfunction is defined as the inability to attain or sustain a penile erection sufficient for satisfactory sexual performance. Tadalafil is not a cure but provides symptomatic relief by improving blood flow.
For benign prostatic hyperplasia, tadalafil reduces symptoms such as urinary urgency, weak stream, and frequent urination. A meta-analysis confirms that tadalafil provides symptom relief comparable to tamsulosin with fewer adverse effects.
For pulmonary arterial hypertension, tadalafil improves exercise capacity by reducing pulmonary vascular resistance.
Tadalista Professional 20mg typically begins to work within 15 to 20 minutes after sublingual administration. Onset time may vary based on metabolic rate, food intake, and general health. Tadalafil is rapidly absorbed and acts by inhibiting the PDE5 enzyme.
The mechanism begins when sexual stimulation triggers nitric oxide (NO) release from penile nerve endings and endothelial cells. NO activates the enzyme guanylate cyclase, which increases cyclic guanosine monophosphate (cGMP) production. cGMP relaxes smooth muscle in the corpus cavernosum, allowing blood to flow into the penis and cause an erection.
PDE5 breaks down cGMP, limiting the duration of an erection. Tadalafil inhibits PDE5, preserving cGMP levels and prolonging muscle relaxation and penile engorgement. However, tadalafil requires sexual arousal to initiate this biochemical cascade. Without sexual stimulation, tadalafil has no effect.
Tadalafil has a half-life of approximately 17.5 hours, which is significantly longer than that of sildenafil or vardenafil. This contributes to its prolonged duration of action and makes it suitable for daily or intermittent use in various conditions.
The effects of Tadalista Professional 20mg can last up to 36 hours. Duration may vary depending on age, overall health, and individual tolerance. Peak plasma concentrations are reached within two hours of dosing, and its extended half-life of 17.5 hours allows for a prolonged therapeutic window. Sexual stimulation is still required during this period for the drug to be effective.
The typical dosage of Tadalista Professional is 20mg taken once within a 24-hour period, approximately 15 to 20 minutes before planned sexual activity. This dose should not be exceeded. Always follow your healthcare provider’s recommendations, as individual adjustments may be required based on response and tolerability.
Swallow the tablet whole with water. Tadalista Professional 20mg may be taken with or without food. For faster results, it is best taken on an empty stomach. Avoid heavy or fatty meals before consumption, as they can delay the drug’s absorption and reduce efficacy. Take it at least one hour before intended sexual activity to ensure optimal performance.
Tadalista Professional 20mg may cause side effects. Most are mild or moderate and diminish over time.
Common Side Effects:
Less Common Side Effects
Rare Side Effects:
Seek immediate medical attention if any serious or persistent effects occur.
Tadalista Professional 20mg can interact with medications that affect blood pressure or liver enzymes. The table below outlines potential drug interactions.
Drug Class or Substance | Interaction Effect |
---|---|
Nitrates (e.g., nitroglycerin) | Severe hypotension; contraindicated |
Alpha-blockers (e.g., tamsulosin) | Additive hypotensive effects |
Antihypertensives (e.g., amlodipine, enalapril) | Mild blood pressure reduction |
Alcohol | Enhanced vasodilation, dizziness, hypotension |
CYP3A4 Inhibitors (e.g., ketoconazole, ritonavir) | Increased tadalafil exposure, risk of toxicity |
CYP3A4 Inducers (e.g., rifampin, phenytoin) | Decreased tadalafil effectiveness |
Antacids (e.g., magnesium hydroxide) | Slower absorption, unchanged total exposure |
CYP Substrates (e.g., theophylline, warfarin) | No significant pharmacokinetic change |
Tadalista Professional 20mg can be taken with or without food. However, consuming a high-fat meal may delay its onset. Alcohol should be avoided or used in moderation. Large quantities of alcohol can reduce drug efficacy and increase the risk of side effects such as dizziness, headache, and low blood pressure.
Follow the storage instructions listed below to ensure the maximum potency of your drug.
Published on: June 2, 2025
Last Modified on: July 15, 2025
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