How does it Work?
Vidalista 20mg contains the active ingredient tadalafil. It belongs to a group of drugs called PDE5 inhibitors.
When a person is sexually stimulated, a molecule called nitric oxide (NO) is released within the penis. This increases levels of another molecule called the cGMP. cGMP causes the smooth muscles inside the penis to relax.
As a result, the blood vessels open wider allowing for blood to flow. It causes the corpus cavernosa (the spongy tissue in the penis) to swell. Thus, the penis becomes larger and stiff enough for sexual intercourse.
However, an enzyme called PDE5 breaks down cGMP molecules, ending the erection. PDE5 inhibitors such as tadalafil stop PDE5 from working too quickly. It prevents the cGMP breakdown. Hence, the action of nitric oxide is enhanced, promoting blood flow. This helps prolong the erection, making it firm enough for satisfactory intercourse.
Note that Vidalista itself does not directly cause an erection. It helps the body respond better to sexual arousal. A person needs to be sexually stimulated for Vidalista to work.
Tadalafil lasts longer than PDE5 inhibitors such as sildenafil. Sildenafil (e.g., Viagra) remains in effect for 4 to 6 hours. Tadalafil (Vidalista) may help men achieve erections for up to 36 hours.
Uses
- Erectile Dysfunction (ED):
Difficulty getting or keeping an erection suitable for sex.
- Benign Prostatic Hyperplasia (BPH):
A benign condition in which the prostate gland is larger than usual. Men with this BPH may have problems with urination. Benign means it’s not cancer.
- Pulmonary Arterial Hypertension (PAH):
A type of high blood pressure that affects the lungs.
Recommended Dose
The recommended dosage of Vidalista 20mg is a tablet once a day. If you take it as required for ED, take it 30 minutes to 1 hour before sex. Take the tablet as a whole; swallow it with a glass of water. It can be taken with or without food.
Do not take 2 doses of generic Vidalista at the same time. Do not take an extra dose or more than one tablet in 24 hours.
For treating other conditions, take Vidalista as prescribed. Doses can vary as per your response to the medicine. Ask your doctor how often you should take it. Stick to the prescribed dosage and frequency to get optimal results.
Missed Dose
For erectile dysfunction, Vidalista 20mg is taken when needed. So, there is little chance of missing a dose. If you’re not sure if you took a pill or skipped a dose by mistake, do not take another one in 24 hours.
For other conditions like BPH, if you miss a dose, take it as soon as you remember. If you remember at a time close to your next dose, skip the missed dose. Continue the next doses as usual.
Overdose
Like any medication, tadalafil can cause harm when taken too much. The medication is meant to have an effect on blood pressure. Taking too much may pose serious risks to your circulation and whole body. Do not take extra doses to get faster results. If an overdose occurs, seek medical help right away.
Side Effects
The most commonly reported side effects of Vidalista 20mg are:
- headache
- indigestion
- heartburn
- nausea
- diarrhea
- flushing (a sudden hot, uneasy feeling in the skin)
- pain in the stomach, muscles, back, arms, or legs
- cough
In rare cases, more serious side effects can occur including:
- loss of vision
- blurred vision
- changes in color vision
- loss of hearing
- ringing in ears
- painful erection that lasts longer than 4 hours
- dizziness
- chest pain
Safety Advice
- Vidalista 20mg should be taken as advised by your physician.
- Do not take this medicine if you are allergic to tadalafil.
- Vidalista 20mg should not be taken while taking certain medicines. Ask your doctor about any possible drug interactions.
- Read the label. Check all information carefully before beginning the medicine.
- Discuss with a doctor if you wish to take it on a regular basis. They should know your full medical history e.g., if you had:
- heart disease
- stroke
- low blood pressure
- liver or kidney problems
- bleeding disorders
- any other health conditions
- Vidalista may make you feel dizzy or affect your vision. Do not drive or operate heavy machinery while taking it.
- Alcohol itself can make it more difficult to get an erection. It may change how well your medicine works and cause side effects. Avoid having large amounts of alcohol If you’re taking it for ED.
- Do not have it with grapefruit juice. Grapefruit juice can interact with medicines.
- Vidalista 20mg is not approved to be used by women or children.
- If you see any side effects, and they get worse over time, seek emergency care.
Medical Interactions
Certain medications do not work well together with Vidalista 20mg. Know your medicines and use caution to avoid drug interactions. Make sure your doctor is aware of all the medicines and supplements you are taking. This may include:
- prescription drugs
- over-the-counter (OTC) medications
- vitamins
- herbs
- any other supplement
Vidalista 20mg can interact with:
- nitrates or diltiazem (both are used to treat patients with angina)
- alpha-blockers (i.e., those given for hypertension)
- some antifungals such as fluconazole
- aprepitant (helps with nausea and vomiting);
- bosentan (or other medications for high blood pressure);
- carbamazepine (relieves nerve pain);
- antibiotic such as clarithromycin, erythromycin
- efavirenz (treats and prevents HIV/AIDS);
- HIV protease inhibitors
- other medications for erectile dysfunction
- other medications for PAH
- anxiety-relieving medicines such as phenobarbital
- antidepressant medications such as sertraline
This is not an exhaustive list, but it shows possible drug interactions. When in doubt, ask a pharmacist or doctor.
Storage
- Vidalista 20mg should be stored at room temperature.
- Keep the tablets in their original packaging. Do not mix with other medicines.
- Store it in a dark, dry place, away from the bathroom or sink. Excessive heat, air, light, and moisture can damage the pills.
- Keep it out of children’s or pet’s reach.
- Always read the label first before you use a medicine. Check the expiry date printed on the label. Discard old, expired medicines or those no longer needed. Use your local waste disposal guidelines to safely dispose of them. Do not flush the pills down the toilet.
FAQs
-
Is Vidalista 20mg (tadalafil) safe for everyone?
Tadalafil is a safe and well-tolerated medicine for men with ED. Even so, the same medicine may not help all persons the same way. Doctors may recommend starting with lower doses in certain cases, e.g., for elderly men.
Ask a doctor in case you are already taking some medicines (e.g., nitrates). Or, if you have any other health conditions. For example, liver or kidney diseases, heart problems, chest pain, etc.
-
What is the most common side effect of tadalafil?
Common side effects include:
- headache
- flushing
- dizziness
- stomach upset
- back pain
- muscle ache
- stuffy nose
In general, it takes time for your body to adjust to the medicine. If any side effects last or get worse, call your doctor without delay.
-
Can I take Vidalista 20mg tablets with food/alcohol?
Vidalista 20mg can be taken with or without food. But, do not take it while drinking lots of alcohol. Both tadalafil and alcohol can lower the blood pressure. So, taking them together can increase the side effects.
-
How long before sex do I need to take Vidalista 20mg?
It is best to take it an hour before sexual activity.
-
How long does an erection last with Vidalista 20mg?
Vidalista 20mg can be effective for up to 36 hours. Many other medicines have to be taken strictly 30 to 60 minutes before sex. Tadalafil provides better flexibility and convenience. It stays in your system for about 3 days.
However, you’ll need to be sexually aroused for it to work. After you have had sex, the erection should go away. If an erection lasts longer than 4 hours, go to the nearest emergency medical facility.
Refrences
- Coward RM, Carson CC. Tadalafil in the treatment of erectile dysfunction. Ther Clin Risk Manag. 2008 Dec;4(6):1315-30. doi: 10.2147/tcrm.s3336. PMID: 19337438; PMCID: PMC2643112. https://www.dovepress.com/tadalafil-in-the-treatment-of-erectile-dysfunction-peer-reviewed-fulltext-article-TCRM
- Hatzimouratidis K. A review of the use of tadalafil in the treatment of benign prostatic hyperplasia in men with and without erectile dysfunction. Ther Adv Urol. 2014 Aug;6(4):135-47. doi: 10.1177/1756287214531639. PMID: 25083163; PMCID: PMC4054509. https://journals.sagepub.com/doi/10.1177/1756287214531639
- Gong B, Ma M, Xie W, Yang X, Huang Y, Sun T, Luo Y, Huang J. Direct comparison of tadalafil with sildenafil for the treatment of erectile dysfunction: a systematic review and meta-analysis. Int Urol Nephrol. 2017 Oct;49(10):1731-1740. doi: 10.1007/s11255-017-1644-5. Epub 2017 Jul 24. PMID: 28741090; PMCID: PMC5603624.https://link.springer.com/article/10.1007/s11255-017-1644-5
- Frajese GV, Pozzi F, Frajese G. Tadalafil in the treatment of erectile dysfunction; an overview of the clinical evidence. Clin Interv Aging. 2006;1(4):439-49. doi: 10.2147/ciia.2006.1.4.439. PMID: 18046921; PMCID: PMC2699638. https://www.atypon-link.com/DMP/doi/abs/10.2147/ciia.2006.1.4.439
- Wang Y, Bao Y, Liu J, Duan L, Cui Y. Tadalafil 5 mg Once Daily Improves Lower Urinary Tract Symptoms and Erectile Dysfunction: A Systematic Review and Meta-analysis. Low Urin Tract Symptoms. 2018 Jan;10(1):84-92. doi: 10.1111/luts.12144. Epub 2016 Nov 5. PMID: 29341503 https://onlinelibrary.wiley.com/doi/10.1111/luts.12144
- Sofikitis N, Kaltsas A, Dimitriadis F, Rassweiler J, Grivas N, Zachariou A, Kaponis A, Tsounapi P, Paterakis N, Karagiannis A, Skouros S, Giannakis I, Champilomatis I, Paschopoulos M, Daphnis D, Giakoumakis I, R Gabales M, M Chua JB, Lantin Iii PL, Mamoulakis C, Takenaka A. The Effect of PDE5 Inhibitors on the Male Reproductive Tract. Curr Pharm Des. 2021;27(23):2697-2713. doi: 10.2174/1381612826666200226121510. PMID: 32101115. https://www.eurekaselect.com/article/104866
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